Well, researchers
have proven her wrong ‘once again’,
and I love it. 😊
Nature.Com published in September the results of a study
of patients with Spinal Bulbar Muscular Atrophy. Click on the link below to
read the entire study.
UnimpairedNeuropsychological Performance and Enhanced Memory Recall in Patients with SBMA:A Large Sample Comparative Study
Abstract:
“Peculiar
cognitive profile of patients with SBMA has been described by fragmented
literature. Our retrospective study reports the neuropsychological evaluations
of a large cohort of patients in order to contribute towards the understanding
of this field. We consider 64 neuropsychological evaluations assessing mnesic,
linguistic and executive functions collected from 2013 to 2015 in patients
attending at Motor Neuron Disease Centre of University of Padova (Italy)…”
“…the aim of the
present study is to report the neuropsychological evaluation of a large sample
of SMBA patients in order to contribute towards the definition of these patients’
cognitive profile.”
“…administered
brief neuropsychological battery aimed to a fast evaluation of short- and
long-term memory, linguistic abilities and executive functioning (for details
please see methodological section). The tasks’ choice had a clinical finality
and was aimed to assess the integrity of the cognitive functions in order to
eventually consider hinderances to an adequate communication with the doctor,
or that could undermine patients’ compliance in the home management of care…”
Results:
Neuropsychological
findings - “ANCOVA results
showed no statistically significant difference between groups in all the
examined test performance, except for the Babcock Story Recall Test score, in
which patients performed better than control participants, with no relevant
influence of age and education. Education level was instead a statistically
significant covariate for all the other measures, while participants’ age was
found statistically significant for the TMT B-A and the DSf scores only…”
Discussion – “No frank cognitive impairment was found
in our retrospective study on 64 patients with SBMA, as deduced from the scores
of patients on neuropsychological tests, compared with those of healthy male
subjects. Surprisingly, patients showed better performance on the Prose Memory
test score…”
“…This
interpretation nicely fits with the phenomenon of the so called somatic
mosaicism, characterizing this pathology. It implies that the number
of CAG-repeats is not constant in every cell of an individual, but it may vary
across tissues, including the cerebral ones; such an instability is typical of
other neuromuscular diseases…”
Full Disclosure: My ‘wonderful’
wife never said those things. She has questioned my intelligence, however, when
I do something dumb and end up falling.
A Special Thank you: Istvan
Reinhardt sent me the link to the above study.
Image:
The
Dunce Corner
I have a few concerns:
ReplyDelete1) Are you sure you want to prove your wife wrong?
2) A positive answer to #1 could disprove the article.
Thanks for this finding. It's good to know I'm not loosing my intelligence level.
Jay, a good question. Being right happens so few times these days, I look at this as a small victory for husbands across the globe. :-)
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