Wednesday, July 31, 2019

Updated Swallowing Exercises


This last week I saw a Ear, Nose and Throat specialist. He scoped my throat and saw significant atrophy in the sphincter muscles and voice box. Below are a few updated Swallowing Exercises provided by a speech therapist.


Perform each of these exercises 10-20 times in a row.

1. Oral Control Exercises

    a. Using lips and tongue, move straw from left cheek to right cheek.

    b. Place straw at center of lips. Using lips and tongue, move in and out.

2. Pharyngeal Stripping Exercises

    a. Swallow hard, squeezing all your muscles. Pretend you are swallowing an egg.

3. Tongue Base Exercises

    a. Stick tongue out, bite tip with teeth or hold tip with a gauze pad. While doing this, swallow, keeping your tongue anchored.

    b. Pull the tongue into the back of the mouth, keeping tongue tip down. Hold for a slow count of 5.

4. Laryngeal Elevation Exercises

    a. Start to swallow normally. Hold your Adam’s apple up with your neck muscles when it gets to the top. Hold for a slow count of 5.

Here is a link to a video on throat exercises:  https://www.youtube.com/watch?v=ZS_4fO6MxyA&feature=share

Thursday, July 25, 2019

What are SARMs?


I read this post from Tom Edward on the KD - Canada Facebook page: 
I heard back from Dr. Fischbeck last night. So SARMS are under active development for SBMA. We studied ASC- JM 17 and a lab in Tawain just received FDA approval to initiate a clinical trial. Paul Taylor's lab at St. Jude's did a study in mice and they were shown to be effective and at least 2 companies are interested in developing the drug. Diane Merry a researcher at Thomas Jefferson in Philadelphia is also working in the lab with other SARMS for SBMA. So it is having some positive results in the mice now let's hope it could translate into us humans.
So, I looked up SARMs and this is what I found...


Selective androgen receptor modulators or SARMs ...

are a novel class of androgen receptor ligands. They are intended to have the same kind of effects as androgenic drugs but be much more selective in their action, allowing them to be used for more uses than the relatively limited legitimate uses of anabolic steroids.

They are intended to have the same kind of effects as androgenic drugs but be much more selective in their action,[1] allowing them to be used for more uses than the relatively limited legitimate uses of anabolic steroids.
Ref:  Wikipedia

Current Uses: Hypogonadism; Osteopenia; Osteoporosis; Sarcopenia; Cachexia

SARMs are not approved by the Food and Drug Administration (FDA) for human use, They are illegally marketed and sold as dietary supplements, and they are banned in all professional and college sports. “SARMs are synthetic drugs that have negative effects similar to those of anabolic steroids, [Google Search of SARMs]